Marquez Valdes-Scantling was originally drafted by the Green Bay Packers in the fifth round of the 2018 NFL Draft, the 174th overall selection.
Valdes-Scantling was most recently with the San Francisco 49ers, signing with their practice squad prior to the start of the 2025 season. He appeared in five games for the 49ers, with four receptions for 40 yards. He was eventually placed on the Reserve/Injured List.
In eight seasons he has appeared in 111 games with the Packers (2018-21), Kansas City Chiefs (2022-23), Buffalo Bills (2024), New Orleans Saints (2024) and San Francisco 49ers (2025). He has 209 receptions for 3,606 yards and 20 touchdowns. He also has 10 carries for 52 yards.
Valdes-Scantling has appeared in 11 postseason games, starting seven, with 24 receptions for 406 yards and four touchdowns.
He began his college career at North Carolina State, before transferring to South Florida for two seasons.