-Running back DeAngelo Williams recorded his 20th career regular season 100-yard rushing game. Williams finished the night with 21 carries for 127 yards. It was Williams first 100-yard rushing game since September 22, 2013. Williams also added one reception for five yards.
- Wide receiver Antonio Brown extended his NFL record streak to 33 consecutive games with at least five receptions for 50 yards. Brown also now has 19 consecutive games with at least five catches for 70 yards, also an NFL record. Brown finished the night with 9 receptions for 133 yards, his 17th 100-yard receiving game.
- Tight end Heath Miller finished the night with eight receptions for 84 yards. It's the 51st time he has had at least 50 receiving yards in a regular season game, ranking him third among active NFL tight ends. Miller also moved into second place on the Steelers' all-time reception list.
- Rookie Bud Dupree got his first career sack early in the first quarter when he got to quarterback Tom Brady for no gain.
- Will Johnson scored his first career rushing touchdown, a one-yard run in the third quarter.
The Pittsburgh Steelers kicked off the 2015 NFL Season against the New England Patriots in Foxborough, Massachusetts.